Koenigs-Knorr synthesis of cycloalkyl glycosides.
نویسندگان
چکیده
Cadmium carbonate was found to be a useful promoter in the Koenigs-Knorr synthesis of 2-(4-methoxybenzyl)cyclohexyl-beta-D-glycopyranosides. Using this promoter model glucoside and galactoside derivatives of cyclic (i.e., secondary) alcohols were synthesized in 50-60 % overall yields. Diastereoisomeric mixtures of products were obtained in these syntheses, which started from racemic isomers of 2-(4-methoxy-benzyl)cyclohexanol. The prepared compounds have been purified and characterized by their (1)H- and (13)C-NMR spectra, as well as by their IR and MS spectra, in order to use them as reference compounds in planned subsequent research.
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ورودعنوان ژورنال:
- Molecules
دوره 9 11 شماره
صفحات -
تاریخ انتشار 2004